Kerala is fighting a health challenge that has put the public and authorities on red alert — the outbreak of Naegleria fowleri, also referred to as the “brain-eating amoeba.” 69 confirmed cases and 19 fatalities have been reported so far in the state, the state health minister told the assembly.
In contrast to past years when outbreaks had been traced to one source of contaminated water, today’s situation is even more alarming. Here, the cases are isolated and dispersed, and health authorities find containment and measures to prevent them very challenging. With a nearly always lethal consequence, public awareness and vigilance are the most potent armaments against this tiny but lethal organism.
What is the Brain-Eating Amoeba, Anyway?
Naegleria fowleri is a microscopic, free-living amoeba that naturally exists in warm, freshwater environments such as lakes, rivers, ponds, and poorly serviced water tanks. Naegleria feeds on bacteria and typically inhabits bottom sediment of these water bodies.
The infection begins when contaminated water enters the body through the nose usually during swimming, diving, or showering. Once inside the body, the amoeba is transported up the olfactory nerve to the brain, causing Primary Amoebic Meningoencephalitis (PAM).
Of 47 known species of Naegleria, only Naegleria fowleri causes PAM, which spreads quickly and almost always leads to death within 3 to 7 days if left untreated.
The good news is that the amoeba:
- Cannot survive in seawater, so oceans and seas are safe.
- Does not get passed from person to person, so it is non-communicable.

Why This Infection is Difficult for Kerala
Health Minister Veena George clarified that the current case is different from previous cases.
- Previous outbreaks were all identified as having been caused by one water source that was contaminated.
- The 2025 cases are, however, dispersed and sporadic with no apparent epidemiologic pattern.
This renders it extremely hard for health authorities to monitor and contain the spread. It suggests that the amoeba may be present in different freshwater bodies of Kerala.
Considering Kerala’s hot climate and widespread usage of freshwater ponds and lakes for bathing, swimming, and household needs, the risk multiplies.
Symptoms of Naegleria Fowleri Infection
The biggest challenge is that the initial symptoms are similar to common brain infections like meningitis, so it’s challenging to diagnose in time.
Early symptoms (1–7 days after exposure):
- High fever
- Severe headache
- Stiff neck
- Nausea and vomiting
Progressive symptoms (as infection worsens):
- Confusion
- Loss of balance
- Seizures
- Hallucinations
- Coma
The illness advances so rapidly that many patients die within a week of developing symptoms, even with medical care.

Incubation Period
The incubation period is normally 1-14 days since exposure. The symptoms may start harmless but gradually worsen. Because of this limited window, early diagnosis and treatment are the utmost priority for any chance of survival.
What Makes It So Deadly?
Naegleria fowleri is one of the deadliest infections for several reasons:
- Rapid Progression – The infection destroys brain tissue within days.
- Misdiagnosis – Early symptoms resemble common viral illnesses.
- Limited Treatment Options – There are few drugs that are effective, and survival rates are still extremely low.
- Environmental Prevalence – Fresh water is readily available in Kerala.
- High Fatality Rate – The global rate of survival for patients afflicted with PAM is less than 5%.
Treatment and Survival Rates
There is no guaranteed cure for Naegleria fowleri infection yet.
- Physicians in Kerala are administering patients miltefosine, an anti-parasitic drug.
- This has had limited gains in the survival rates, but still, mortality remains very high.
- Antifungal and antibiotic regimen combinations are other treatments, but these are not common.
Early identification and aggressive treatment are the significant factors at play. Sadly, once patients show definite symptoms, the disease is already well entrenched.
Prevention is the Best Defense
Since vaccines or effective cures are not available, prevention is inevitable. Health officials recommend the following preventive measures:
- Avoid swimming in warm, calm freshwater like ponds, rivers, or lakes.
- Keep water tanks — clean and chlorinate them on a regular basis.
- Avoid disturbing sediment in shallow freshwater habitats where amoeba is present.
- Use nose clips or keep your head out of water when swimming in freshwater.
- Get immediate medical attention if you have a fever, headache, or confusion following exposure to freshwater.
These precautions can drastically lower the risk of exposure.
Why Kerala Needs Extra Care
Geographical conditions and life style of Kerala put it in greater risk:
- Abundant fresh water sources used for ordinary purposes.
- Nursery-love warm tropical climate is particularly suitable for amoeba growth.
- River bathing as a culture increases exposure risk.
- Water sports and tourism in lakes and rivers draw thousands of people daily.
Unless proper water cleanliness and monitoring policies are enforced, the infection can continue to appear in sporadic cases.
Global Perspective: Naegleria Fowleri Beyond Kerala
Though Kerala is in focus at present, Naegleria fowleri is not exclusive to India. The infection has also been reported in the US, Pakistan, Australia, and some other countries.
In the US, infections are mostly found during summer in southern states where freshwater bodies get heated up. Karachi, Pakistan, also has repeated cases of infections where water sanitation is an issue.
This indicates that the amoeba survives in identical conditions across the globe, posing a threat to global health.
Public Awareness is Paramount
Lack of public awareness is one of the biggest challenges in preventing this disease. Individuals continue to swim or use freshwater unaware of the risks.
- The populations must be educated regarding the dangers of stagnant warm water.
- Public health campaigns must prioritize water chlorination and hygiene.
- Medical professionals must be informed of early symptoms and act swiftly.
It is only through collective efforts by the government, medical professionals, and the public that the impact of this deadly amoeba can be reduced.
Conclusion
The Kerala Naegleria fowleri outbreak with 69 cases and 19 deaths is a stark reminder of the vulnerability of humans to small microorganisms.
Unlike the earlier years, the sporadic nature of the cases has impeded containment. In the absence of a certain cure, prevention and quick medical attention are the only bulwarks against this “brain-eating amoeba.”
By avoiding risky freshwater contact, adhering to water hygiene, and spreading awareness, Kerala — and the world — can reduce the devastation of this rare but deadly infection.
Frequently Asked Questions (FAQs)
1. What is Kerala’s brain-eating amoeba?
Kerala’s brain-eating amoeba is called Naegleria fowleri. It is a micro parasite found in warm freshwater such as ponds, lakes, and rivers. When water that is contaminated enters the nostril, it may reach the brain and cause a very rare but deadly infection known as Primary Amoebic Meningoencephalitis (PAM).
2. How many brain-eating amoeba cases in Kerala?
So far, Kerala has seen 69 cases and 19 deaths due to Naegleria fowleri infection. Unlike the earlier outbreaks involving single water sources, the new cases are scattered, which renders containment very tough.
3. What are the early symptoms of Naegleria fowleri infection?
Early symptoms appear 1 to 14 days post-exposure and include:
- Severe headache
- Sudden high fever
- Nausea and vomiting
- Stiff neck
As the infection progresses, patients may develop confusion, seizures, and even coma.
4. Can the brain-eating amoeba be transmitted from human to human?
No. Naegleria fowleri is not infectious. It can’t be transmitted from human to human, nor can it be spread by consuming contaminated water. Infection occurs only when amoeba-contaminated water enters the nose.
5. Is any treatment available for Naegleria fowleri in Kerala?
Treatment is now extremely limited. Kerala physicians are using miltefosine, an anti-parasitic medication, and antifungal and antibiotic combinations. The survival rate continues to be very low, and early medical treatment is the most important factor.
6. How is brain-eating amoeba infection prevented?
- Prevention is the key:
- Don’t swim in hot, stagnant freshwater.
- Use chlorinated, clean water tanks.
- Don’t disturb sediment in shallow water.
- Use nose clips when swimming.
- Ask for medical attention if symptoms develop after freshwater exposure.